Is GTA 6 Set in the Same Universe as GTA 5?

Yes, Part of the HD Universe

GTA 6 is set within the HD Universe, the same continuity established by Grand Theft Auto IV and Grand Theft Auto V.

Rockstar Games has maintained a distinct separation between its universes: the 2D Universe (GTA 1 & 2), the 3D Universe (GTA 3, Vice City, San Andreas), and the HD Universe (GTA 4, GTA 5, and now GTA 6). Locations, events, and characters from the HD Universe follow their own canon and are separate from previous iterations.

While Vice City returns in GTA 6, it is a reimagined version within the HD Universe, distinct from the city seen in the 3D Universe.

Official Sources

Rockstar Games – Official GTA VI Page
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